Victoria Roberton

Postdoctoral Research Fellow

Project: Improving nerve grafting using biomaterials

Victoria received a first class honours degree in Psychology (BSc) from the University of Surrey (2009), including a professional placement year in the School of Psychology at Cardiff University carrying out behavioural neuroscience research in rodent models of Alzheimer’s disease.  Following this she was awarded a Wellcome Trust PhD studentship in Integrative Neuroscience (2009-2014), carrying out 3 lab rotations at Cardiff University before her PhD project in the Brain Repair Group with Professors Anne Rosser and Stephen Dunnett. Victoria’s PhD and first post-doctoral position at Cardiff included research into cell therapies for Huntington’s disease and Parkinson’s disease, testing neuronal transplants in rodent models of disease and studying the integration, immune response and function of these grafts. Additional work included management of a fetal tissue bank at Cardiff for research and clinical use in the TransEuro trial for fetal tissue transplantation co-ordinated by Cambridge University.

Victoria joined UCL in 2016 in the Department of Biochemical Engineering, studying a candidate line of olfactory ensheathing cells for transplantation in spinal cord injury. In 2019, with Dr James Phillips, she received the UCL Rosetrees Stoneygate Prize to develop novel methods of mediating the immune response to peripheral nerve transplants using biomaterials, in collaboration with Dr Gareth Williams (UCL School of Pharmacy), Dr Ashleigh Boyd (UCL Division of Surgery & Interventional Science) and Dr Rebecca Shipley (UCL Mechanical Engineering)

CONTACT:

Email: v.roberton@ucl.ac.uk

Twitter: @Vickoirr

PREVIOUS APPOINTMENTS

Sep 2016-Nov 2018: Research Associate – UCL Department of Biochemical Engineering (Dr. Ivan Wall)

Jan 2014 – Sep 2016: Research Associate and Cardiff Fetal Tissue Bank Manager – Cardiff University Brain Repair Group (Prof. Anne Rosser and Prof. Stephen Dunnett)


QUALIFICATIONS:

PhD in Integrative Neuroscience – 2009-2014

First class BSc (Hons) in Psychology – 2005-2009 (including professional placement year in behavioural neuroscience research at Cardiff University School of Psychology)

PRIZES & AWARDS:

·       UCL Rosetrees Stoneygate Prize 2019 – with Dr James Phillips, Dr Gareth Williams, Dr Ashleigh Boyd and Dr Rebecca Shipley

·       Travel award to attend NECTAR 2015 (Lund, Sweden)

·       Travel award to attend NECTAR 2014 (Galway, Ireland)

·       Travel grant from Guarantors of Brain to attend FENS Forum of Neuroscience 2012 (Barcelona)

·       Wellcome Trust Integrative Neuroscience PhD studentship, 2009-2013

·       University of Surrey Mark Bradshaw Memorial Prize for best Psychology undergraduate dissertation, 2009

PUBLICATIONS (https://orcid.org/0000-0002-0404-6984)

Georgiou, M., Reis, J.N. dos, Wood, R., Esteban, P.P., Roberton, V., Mason, C., Li, D., Li, Y., Choi, D., Wall, I., 2018. Bioprocessing strategies to enhance the challenging isolation of neuro-regenerative cells from olfactory mucosa. Sci. Rep. 8, 14440. doi:10.1038/s41598-018-32748-w

Roberton VH, Rosser AE., McGorrian AM., Precious SV. Dissection and preparation of human primary fetal ganglionic eminence tissue for research and clinical application. Methods in Molecular Biology (in press)

Harrison D.J., Roberton V.H., Vinh N.N., Brooks S.P., Dunnett S.B., Rosser A.E.The effect of tissue preparation and donor age on striatal graft morphology in the mouse. In press (Cell Transplantation)

Kalbassi, S., Bachmann, S. O., Cross, E., Roberton, V. H., & Baudouin, S. J. (2017). Male and Female Mice Lacking Neuroligin-3 Modify the Behavior of Their Wild-Type Littermates. eNeuro, 4(4), ENEURO.0145-17.2017. https://doi.org/10.1523/ENEURO.0145-17.2017

Lelos M.J., Roberton V.H, Vinh N.N., Harrison, C., Eriksen, P., Torres, E. M., Clinch, S. P., Rosser, A. E., Dunnett, S. B. (2016) Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function. Cell Transplantation, 25(4):665-75

Roberton, V.H., Rosser, A.E., Kelly, C.M. (2015) Neonatal desensitisation for the study of regenerative medicine. Regenerative Medicine, 10:3, 265-274

Roberton, V.H., Evans, A.E., Harrison, D.J., Precious, S.V., Dunnett, S.B., Kelly, C.M., Rosser, A.E. (2013). Is the adult mouse striatum a hostile host for neural transplant survival? NeuroReport, 24(18), 1010–1015

Harris, A. D., Roberton, V. H., Huckle, D. L., Saxena, N., Evans, C. J., Murphy, K., Hall, J. E. et al. (2013). Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxia. Journal of Magnetic Resonance Imaging 37:739-745

Kelly, C. M., Roberton, V. H., Dunnett, S. B. and Rosser, A. E. (2012). Reply to “Neonatal desensitization does not universally prevent xenograft rejection”. Nat Meth 9:858-858

Mattsson, N., Evans, A., Rosser, A., Roberton, V., Battersby, A., Fox, S. and Huot, P. (2012). Journal Watch: Our panel of experts highlight the most important research articles across the spectrum of topics relevant to the field of neurodegenerative disease management. Neurodegenerative Disease Management 2:569-572

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