Novel inhibitors of AChE and Aβaggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer’s disease

Novel inhibitors of AChE and Aβaggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer’s disease

Y Liu, G Uras, I Onuwaje, W Li, H Yao, S Xu, X Li, X Li, J Phillips, S Allen, Q Gong, H Zhang, Z Zhu, J Liu & J Xu (2022). Novel inhibitors of AChE and Aβaggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer’s disease. European Journal of Medicinal Chemistry, […]

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In silico framework to inform the design of repair constructs for peripheral nerve injury repair

S Laranjeira, G Pellegrino, KS Bhangra, JB Phillips & RJ Shipley (2022). In silico framework to inform the design of repair constructs for peripheral nerve injury repair. J R Soc Interface, 19, 20210824

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An alginate-based encapsulation system for delivery of therapeutic cells to the CNS

D. Eleftheriadou, R.E. Evans, E. Atkinson, A. Abdalla, F.K.H. Gavins, A.S. Boyd, G.R. Williams, J.C. Knowles, V.H. Roberton & J.B. Phillips (2022). An alginate-based encapsulation system for delivery of therapeutic cells to the CNS. RSC Adv. 12, 4005-4015

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A shock to the (nervous) system: Bioelectricity within peripheral nerve tissue engineering

R.P. Trueman, A. S. Ahlawat & J. B. Phillips (2021). A shock to the (nervous) system: Bioelectricity within peripheral nerve tissue engineering. Tissue Engineering Part B: Reviews http://doi.org/10.1089/ten.TEB.2021.0159

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Volumetric MRI is a promising outcome measure of muscle reinnervation

M Wilcox, L Dos Santos Canas, R Hargunani, T Tidswell, H Brown, M Modat, J Phillips, S Ourselin & T Quick (2021). Volumetric MRI is a promising outcome measure of muscle reinnervation. Sci Rep 11, 22433 (2021). https://doi.org/10.1038/s41598-021-01342-y

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Engineered neural tissue made using clinical-grade human neural stem cells supports regeneration in a long gap peripheral nerve injury model

M.L.D. Rayner, A.G.E. Day, K.S. Bhangra, J. Sinden & J.B. Phillips (2021). Engineered neural tissue made using clinical-grade human neural stem cells supports regeneration in a long gap peripheral nerve injury model. Acta Biomaterialia https://doi.org/10.1016/j.actbio.2021.08.030

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Repurposing Small Molecules to Target PPAR-γ as New Therapies for Peripheral Nerve Injuries

M.L.D. Rayner, J. Healy & J.B. Phillips (2021). Repurposing Small Molecules to Target PPAR-γ as New Therapies for Peripheral Nerve Injuries. Biomolecules 2021, 11, 1301

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‘EngNT’ — Engineering live neural tissue for nerve replacement

J.B. Phillips (2021) ‘EngNT’ — Engineering live neural tissue for nerve replacement. Emerging Topics in Life Sciences ETLS20210085

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Modelling-informed cell-seeded nerve repair construct designs for treating peripheral nerve injuries

R. Coy, M. Berg, J.B. Phillips & R.J. Shipley (2021) Modelling-informed cell-seeded nerve repair construct designs for treating peripheral nerve injuries. PLoS Computational Biology 17, e1009142

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Natural biomaterials as instructive engineered microenvironments that direct cellular function in peripheral nerve tissue engineering

R. Powell, D. Eleftheriadou, S. Kellaway & J.B. Phillips (2021) Natural biomaterials as instructive engineered microenvironments that direct cellular function in peripheral nerve tissue engineering. Front. Bioeng. Biotechnol. 9:674473

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