Publications
Some of our recent publications are listed below. To find more please visit UCL IRIS
Latest Papers
Automated production of nerve repair constructs containing endothelial cell tube-like structures
Added 23 November, 2024
PO Smith, G Huang, K Devries, SN Nazhat & JB Phillips (2024) Automated production of nerve repair constructs containing endothelial cell tube-like structures. Biofabrication 17 https://doi.org/10.1088/1758-5090/ad8efd
Biofabrication and biomanufacturing in Ireland and the UK
Added 23 November, 2024
JF Murphy, M Lavelle, L Asciak, R Burdis, HJ Levis, C Ligorio, J McGuire, M Polleres, PO Smith, L Tullie, J Uribe-Gomez, B Chen, JI Dawson, JE Gautrot, NM Hooper, DJ Kelly, VSW Li, A Mata, A Pandit, JB Phillips, W Shu, MM Stevens, RL Williams, JPK Armstrong & YYS Huang (2024) Biofabrication and biomanufacturing in Ireland and the UK. Bio-Design and Manufacturing https://doi.org/10.1007/s42242-024-00316-z
In silico model for automated calculation of functional metrics in animal models of peripheral nerve injury repair
Added 11 October, 2024
S Laranjeira, O Guillemot-Legris, G Girmahun, V Roberton, JB Phillips, RJ Shipley (2024) In silico model for automated calculation of functional metrics in animal models of peripheral nerve injury repair.
Computers in Biology and Medicine 181, 109036 https://doi.org/10.1016/j.compbiomed.2024.109036
Formation of vascular-like structures using a chemotaxis-driven multiphase model
Added 11 October, 2024
G Al-Badri, JB Phillips, RJ. Shipley & NC Ovenden (2024) Formation of vascular-like structures using a chemotaxis-driven multiphase model. Mathematical Biosciences 372, 109183 https://doi.org/10.1016/j.mbs.2024.109183
Aligned Bioelectronic Polypyrrole/Collagen Constructs for Peripheral Nerve Interfacing
Added 3 March, 2024
RP Trueman, O Guillemot-Legris, HT Lancashire, AS Mehta, J Tropp, RE Daso, J Rivnay, AB Tabor, JB Phillips & BC Schroeder (2024). Aligned Bioelectronic Polypyrrole/Collagen Constructs for Peripheral Nerve Interfacing. Advanced Engineering Materials, e2301488. 10.1002/adem.202301488.
Electrospun polyvinylidene fluoride with novel facile synthesized functionalized boron nitride quantum dots for neural applications
Added 3 March, 2024
B Ekram, RP Trueman, JB Phillips, H Ros, BM Abd El-Hady, D El-Gendy (2024) Electrospun polyvinylidene fluoride with novel facile synthesized functionalized boron nitride quantum dots for neural applications. Polymer Engineering and Science 10.1002/pen.26632.
Electrospun aligned tacrolimus-loaded polycaprolactone biomaterials for peripheral nerve repair
Added 12 October, 2023
HN Gregory, O Guillemot-Legris, D Crouch, G Williams & JB Phillips (2023) Electrospun aligned tacrolimus-loaded polycaprolactone biomaterials for peripheral nerve repair. Regenerative Medicine https://doi.org/10.2217/rme-2023-0151
Development of ibuprofen-loaded electrospun materials suitable for surgical implantation in peripheral nerve injury
Added 12 October, 2023
K Dziemidowicz, SC Kellaway, O Guillemot-Legris, O Matar, R Pereira Trindade, VH Roberton, MLD Rayner, GR Williams & JB Phillips (2023) Development of ibuprofen-loaded electrospun materials suitable for surgical implantation in peripheral nerve injury. Biomaterials Advances 154, 213623, https://doi.org/10.1016/j.bioadv.2023.213623
Mathematical modelling with Bayesian inference to quantitatively characterize therapeutic cell behaviour in nerve tissue engineering
Added 12 October, 2023
M Berg, D Eleftheriadou, JB Phillips & RJ Shipley (2023) Mathematical modelling with Bayesian inference to quantitatively characterize therapeutic cell behaviour in nerve tissue engineering. Journal of the Royal Society Interface, 20 (206), 20230258. 10.1098/rsif.2023.0258.
Local Administration of Minocycline Improves Nerve Regeneration in Two Rat Nerve Injury Models
Added 30 July, 2023
O Guillemot-Legris, G Girmahun, RJ Shipley & JB Phillips (2023). Local Administration of Minocycline Improves Nerve Regeneration in Two Rat Nerve Injury Models. Int J Mol Sci 24, 12085
Serum neurofilament light chain measurements following nerve trauma
Added 30 July, 2023
M Wilcox, MLD Rayner, O Guillemot-Legris, I Platt, H Brown, T Quick & JB Phillips (2023). Serum neurofilament light chain measurements following nerve trauma. J Peripher Nerv Syst. https://doi.org/10.1111/jns.12576
Improving the biological interfacing capability of diketopyrrolopyrrole polymers via p-type doping
Added 30 July, 2023
RP Trueman, PG Finn, MM Westwood, A Dey, R Palgrave, A Tabor, JB Phillips & BC Schroeder (2023). Improving the biological interfacing capability of diketopyrrolopyrrole polymers via p-type doping. J Mater Chem C Mater 11, 6943-6950
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration
Added 28 May, 2023
G Gong, B Bilanges, B Allsop, GR Masson, V Roberton, T Askwith, S Oxenford, RR Madsen, SE Conduit, D Bellini, M Fitzek, M Collier, O Najam, Z He, B Wahab, SH McLaughlin, AWE Chan, I Feierberg, A Madin, D Morelli, A Bhamra, V Vinciauskaite, KE Anderson, S Surinova, N Pinotsis, E Lopez-Guadamillas, M Wilcox, A Hooper, C Patel, MA Whitehead, TD Bunney, LR Stephens, PT Hawkins, M Katan, DM Yellon, SM Davidson, DM Smith, JB Phillips, R Angell, RL Williams & B Vanhaesebroeck (2023). A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature https://doi.org/10.1038/s41586-023-05972-2
Exploring the Effect of Vitamins B1, B6 and B12 on Neurite Regeneration using a 3D Co-Culture Model of Neurodegeneration
Added 19 May, 2023
PO Smith, RP Trueman, R Powell, H Gregory, JB Phillips, P Bohnhorst & MLD Rayner (2023). Exploring the Effect of Vitamins B1, B6 and B12 on Neurite Regeneration using a 3D Co-Culture Model of Neurodegeneration. International Journal of Physical Medicine & Rehabilitation 11, 1000667
Culture Conditions for Human Induced Pluripotent Stem Cell-Derived Schwann Cells: A Two-Centre Study
Added 18 March, 2023
Z Huang, R Powell, S Kankowski, JB Phillips & K Haastert-Talini (2023). Culture Conditions for Human Induced Pluripotent Stem Cell-Derived Schwann Cells: A Two-Centre Study. International Journal of Molecular Sciences 24(6), 5366. https://doi.org/10.3390/ijms24065366
Perspectives on optimizing local delivery of drugs to peripheral nerves using mathematical models
Added 18 March, 2023
S Laranjeira, VH Roberton, JB Phillips, &RJ Shipley (2023). Perspectives on optimizing local delivery of drugs to peripheral nerves using mathematical models. WIREs Mechanisms of Disease, 15( 2), e1593. https://doi.org/10.1002/wsbm.1593
Local delivery of tacrolimus using electrospun poly-ε-caprolactone nanofibres suppresses the T-cell response to peripheral nerve allografts
Added 23 December, 2022
VH Roberton, HN Gregory, U Angkawinitwong, O Mokrane, AS Boyd, RJ Shipley, GR Williams & JB Phillips (2022). Local delivery of tacrolimus using electrospun poly-ε-caprolactone nanofibres suppresses the T-cell response to peripheral nerve allografts. Journal of Neural Engineering https://doi.org/10.1088/1741-2552/acad2a
Exploring the Nerve Regenerative Capacity of Compounds with Differing Affinity for PPARγ In Vitro and In Vivo
Added 23 December, 2022
MLD Rayner, SC Kellaway, I Kingston, O Guillemot-Legris, H Gregory, J Healy & JB Phillips (2022). Exploring the Nerve Regenerative Capacity of Compounds with Differing Affinity for PPARγ In Vitro and In Vivo. Cells 12, 42 https://doi.org/10.3390/cells12010042
Engineered neural tissue made using hydrogels derived from decellularised tissues for the regeneration of peripheral nerves
Added 10 December, 2022
SC Kellaway, V Roberton, JN Jones, R Loczenski, JB Phillips, LJ White (2022). Engineered neural tissue made using hydrogels derived from decellularised tissues for the regeneration of peripheral nerves. Acta Biomaterialia https://doi.org/10.1016/j.actbio.2022.12.003
Discovery of novel hybrids containing clioquinol−1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer’s disease
Added 19 November, 2022
X Li, T Li, P Zhang, X Li, L Lu, Y Sun, B Zhang, S Allen, L White, J Phillips, Z Zhu, H Yao, J Xu (2022). Discovery of novel hybrids containing clioquinol−1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease. European Journal of Medicinal Chemistry 244, 114841
Considerations for the use of biomaterials to support cell therapy in neurodegenerative disease
Added 19 November, 2022
VH Roberton & JB Phillips (2022). Considerations for the use of biomaterials to support cell therapy in neurodegenerative disease. International Review of Neurobiology https://doi.org/10.1016/bs.irn.2022.09.009
A combined experimental and computational framework to evaluate the behavior of therapeutic cells for peripheral nerve regeneration
Added 2 May, 2022
D Eleftheriadou, M Berg, JB Phillips & RJ Shipley (2022). A combined experimental and computational framework to evaluate the behavior of therapeutic cells for peripheral nerve regeneration. Biotechnology & Bioengineering https://doi.org/10.1002/bit.28105
Novel inhibitors of AChE and Aβaggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer’s disease
Added 25 March, 2022
Y Liu, G Uras, I Onuwaje, W Li, H Yao, S Xu, X Li, X Li, J Phillips, S Allen, Q Gong, H Zhang, Z Zhu, J Liu & J Xu (2022). Novel inhibitors of AChE and Aβaggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry, 235, 114305
In silico framework to inform the design of repair constructs for peripheral nerve injury repair
Added 20 March, 2022
S Laranjeira, G Pellegrino, KS Bhangra, JB Phillips & RJ Shipley (2022). In silico framework to inform the design of repair constructs for peripheral nerve injury repair. J R Soc Interface, 19, 20210824
An alginate-based encapsulation system for delivery of therapeutic cells to the CNS
Added 1 February, 2022
D. Eleftheriadou, R.E. Evans, E. Atkinson, A. Abdalla, F.K.H. Gavins, A.S. Boyd, G.R. Williams, J.C. Knowles, V.H. Roberton & J.B. Phillips (2022). An alginate-based encapsulation system for delivery of therapeutic cells to the CNS. RSC Adv. 12, 4005-4015