Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells

Kimani, Stanley ; Shmigol, Tatiana; Hammond, Samantha ; Phillips, James B. ; Bruce, James I. ; MacRobert, Alexander J.; Malakhov, Mikhail V. and Golding, Jon P. (2013). Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and pho…

Micro-structured materials and mechanical cues in 3D collagen gels

Phillips, James and Brown, Robert (2010). Micro-structured materials and mechanical cues in 3D collagen gels. In: Haycock, John W. ed. 3D Cell Culture. Methods in Molecular Biology (695). New York: Humana Press, pp. 183–196.

New Paper: Using a 3D culture model to understand the effect of PDT on neurons

Our paper “Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model” reveals new information about how neurons can survive photodynamic therapy (PDT) cancer treatments. By using a co-culture system that maintained neurons and glial cells in a 3D environment we were able to identify […]

Engineered neural tissue with aligned Schwann cells supports neuronal regeneration in vivo and can be assembled using differentiated adipose-derived stem cells

Georgiou, M. ; Loughlin, J. ; Golding, J. P. ; Kingham, P. J. and Phillips, J. B. (2012). Engineered neural tissue with aligned Schwann cells supports neuronal regeneration in vivo and can be assembled using differentiated adipose-derived stem cell…

Defining glial cell self-alignment parameters for 3D CNS tissue models

O’Rourke, C. M. ; Loughlin, A. J. ; Drake, R. and Phillips, J. B. (2012). Defining glial cell self-alignment parameters for 3D CNS tissue models. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK.

Astrocytes expressing GFP in 3D collagen gels provide an effective model for screening the glial response to potential CNS cell therapies

Johns, N. ; East, E. ; Golding, J. P. ; Loughlin, A. J. and Phillips, J. B. (2012). Astrocytes expressing GFP in 3D collagen gels provide an effective model for screening the glial response to potential CNS cell therapies. In: Annual meeting of t…

Developing a 3D co-culture model to simulate perinatal hypoxic-ischaemic brain injury in preterm infants

Osei, E. T.; Evans, L.; Phillips, J. B. and Loughlin, A. J. (2012). Developing a 3D co-culture model to simulate perinatal hypoxic-ischaemic brain injury in preterm infants. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-…

Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model

Wright, Kathleen E. ; MacRobert, Alexander J. and Phillips, James B. (2012). Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-cultu…