Publications

Some of our recent publications are listed below. To find more please download a complete list of publications or visit Open Research Online or UCL Discovery.

 

Latest Papers

Schwann cells and mesenchymal stem cells in laminin- or fibronectin-aligned matrices and regeneration across a critical size defect of 15 mm in the rat sciatic nerve

Added 27 November, 2017

Gonzalez-Perez F, Hernández J, Heimann C, Phillips JB, Udina E, Navarro X (2017) Schwann cells and mesenchymal stem cells in laminin- or fibronectin-aligned matrices and regeneration across a critical size defect of 15 mm in the rat sciatic nerve. Journal of Neurosurgery: Spine, doi: 10.3171/2017.5.SPINE161100

The Effect of Hypothermic and Cryogenic Preservation on Engineered Neural Tissue

Added 27 November, 2017

Day AGE, Bhangra KS, Murray-Dunning C, Stevanato L, Phillips JB (2017) The Effect of Hypothermic and Cryogenic Preservation on Engineered Neural Tissue. Tissue Engineering Part C Methods, 23, 575-582

Low frequency oscillating gradient spin-echo sequences improve sensitivity to axon diameter: An experimental study in viable nerve tissue

Added 17 September, 2017

Kakkar LS, Bennett OF, Siow B, Richardson S, Ianuş A, Quick T, Atkinson D, Phillips JB & Drobnjak I (2017) Low frequency oscillating gradient spin-echo sequences improve sensitivity to axon diameter: An experimental study in viable nerve tissue. NeuroImage https://doi.org/10.1016/j.neuroimage.2017.07.060

Could clinical photochemical internalisation be optimised to avoid neuronal toxicity?

Added 10 June, 2017

C. O’Rourke, C. Hopper, A.J. MacRobert, J.B. Phillips & J.H. Woodhams (2017) Could clinical photochemical internalisation be optimised to avoid neuronal toxicity? International Journal of Pharmaceutics 528, 133-143

Stabilization, rolling and addition of other ECM proteins to collagen hydrogels improves regeneration in chitosan guides for long peripheral nerve gaps in rats

Added 18 April, 2017

F. Gonzalez-Perez, S. Cobianchi, C. Heimann, J.B. Phillips, E. Udina, X. Navarro (2017) Stabilization, rolling and addition of other ECM proteins to collagen hydrogels improves regeneration in chitosan guides for long peripheral nerve gaps in rats. Neurosurgery 80, 465-474

Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration

Added 22 March, 2017

Caitriona O’Rourke, Charlotte Lee-Reeves, Rosemary AL Drake, Grant WW Cameron, A Jane Laughlin & James B Phillips (2017) Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration. Journal of Tissue Engineering 8, 1-9.

Combining Gene and Stem Cell Therapy for Peripheral Nerve Tissue Engineering

Added 22 March, 2017

Francesca Busuttil, Ahad A. Rahim and James B. Phillips (2017) Combining gene and stem cell therapy for peripheral nerve tissue engineering. Stem Cells and Development 26(4):231-238

Engineered neural tissue with Schwann cell differentiated human dental pulp stem cells: potential for peripheral nerve repair?

Added 6 January, 2017

K. Sanen, W. Martens, M. Georgiou, M. Ameloot, I. Lambrichts & J.B. Phillips (2017) Engineered neural tissue with Schwann cell differentiated human dental pulp stem cells: potential for peripheral nerve repair? Journal of Tissue Engineering and Regenerative Medicine doi: 10.1002/term.2249

An integrated theoretical-experimental approach to accelerate translational tissue engineering

Added 10 November, 2016

R.H. Coy, O.R. Evans, J.B. Phillips & R.J. Shipley (2016). An integrated theoretical-experimental approach to accelerate translational tissue engineering. Journal of Tissue Engineering and Regenerative Medicine doi: 10.1002/term.2346

Biomechanical properties of the spinal cord: implications for tissue engineering and clinical translation.

Added 12 September, 2016

R.D. Bartlett, D. Choi & J.B. Phillips (2016). Biomechanical properties of the spinal cord: implications for tissue engineering and clinical translation. Regenerative Medicine, (doi:10.2217/rme-2016-0065)

Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair

Added 12 September, 2016

K.S. Bhangra, F. Busuttil, J.B. Phillips & A.A. Rahim (2016). Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair. Stem Cells International, ID 7502178

Label-free mapping of microstructural organisation in self-aligning cellular collagen hydrogels using image correlation spectroscopy

Added 21 November, 2015

K. Sanen, R. Paesen, S. Luyck, J.B. Phillips, I. Lambrichts, W. Martens & M. Ameloot (2015) Label-free mapping of microstructural organisation in self-aligning cellular collagen hydrogels using image correlation spectroscopy. Acts Biomaterialia doi: 10.1016/j.actbio.2015.10.047

Embryonic and mature astrocytes exert different effects on neuronal growth in rat ventral mesencephalic slice cultures

Added 21 November, 2015

Hashemian, C. O'Rourke, J.B. Phillips, I. Strömberg & S. Af Bjerkén (2015) Embryonic and mature astrocytes exert different effects on neuronal growth in rat ventral mesencephalic slice cultures. Springerplus doi: 10.1186/s40064-015-1362-3

Optimising contraction and alignment of cellular collagen hydrogels to achieve reliable and consistent engineered anisotropic tissue.

Added 20 October, 2015

O'Rourke, Caitriona; Drake, Rosemary A. L.; Cameron, Grant W. W.; Loughlin, A. Jane and Phillips, James B. (2015). Optimising contraction and alignment of cellular collagen hydrogels to achieve reliable and consistent engineered anisotropic tissue. Journal of Biomaterials Applications (Early view).

Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat sciatic nerve.

Added 11 November, 2014

Melanie Georgiou, Jon P. Golding, Alison J. Loughlin, Paul J. Kingham and James B. Phillips (2015). Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat sciatic nerve. Biomaterials, 37 pp. 242–251.

A three-dimensional collagen construct to model lipopolysaccharide-induced activation of BV2 microglia

Added 7 August, 2014

Haw, Randy Tatt; Tong, Chih Kong; Yew, Andrew; Lee, Han Chung; Phillips, James B. and Vidyadaran, Sharmili (2014). A three-dimensional collagen construct to model lipopolysaccharide-induced activation of BV2 microglia. Journal of Neuroinflammation, 11, article no. 134.

Monitoring neuron and astrocyte interactions with a 3D cell culture system

Added 6 August, 2014

Phillips, James B. (2014). Monitoring neuron and astrocyte interactions with a 3D cell culture system. In: Murray, Andrew J. ed. Axon Growth and Regeneration: Methods and Regeneration. Methods in Molecular Biology: Methods and Protocols, 1162. New York: Springer, pp. 113–124.

Building stable anisotropic tissues using cellular collagen gels

Added 11 February, 2014

Phillips, James B. (2014). Building stable anisotropic tissues using cellular collagen gels. Organogenesis, 10(1) pp. 6–8.

Human dental pulp stem cells can differentiate into Schwann cells and promote and guide neurite outgrowth in an aligned tissue-engineered collagen construct in vitro

Added 23 December, 2013

Martens, Wendy ; Sanen, Kathleen ; Georgiou, Melanie ; Struys, Tom; Bronckaers, Annelies; Ameloot, Marcel; Phillips, James and Lambrichts, Ivo (2014). Human dental pulp stem cells can differentiate into Schwann cells and promote and guide neurite outgrowth in an aligned tissue-engineered collagen construct in vitro. FASEB Journal, 28(4) pp. 1634–1643.

Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro

Added 11 December, 2013

Gromnicova, Radka ; Davies, Heather A. ; Sreekanthreddy, Pedagannganagari ; Romero, Ignacio A. ; Lund, Torben; Roitt, Ivan M.; Phillips, James B. and Male, David K. (2013). Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro. PLoS ONE, 8(12), article no. e81043.

A 3D in vitro model reveals differences in the astrocyte response elicited by potential stem cell therapies for CNS injury

Added 25 October, 2013

East, Emma ; Johns, Noemie ; Georgiou, Melanie ; Golding, Jon ; Loughlin, Jane ; Kingham, Paul and Phillips, James (2013). A 3D in vitro model reveals differences in the astrocyte response elicited by potential stem cell therapies for CNS injury. Regenerative Medicine, 8(6) pp. 739–746.

Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy

Added 24 July, 2013

Golding, J. P. ; Wardhaugh, T. ; Patrick, L.; Turner, M.; Phillips, J. B. ; Bruce, J. I. and Kimani, S. G. (2013). Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy. British Journal of Cancer, 109(4) pp. 976–982.

Engineered neural tissue for peripheral nerve repair

Added 9 July, 2013

Georgiou, Melanie ; Bunting, Stephen C. J. ; Davies, Heather A. ; Loughlin, Alison J. ; Golding, Jonathan P. and Phillips, James B. (2013). Engineered neural tissue for peripheral nerve repair. Biomaterials, 34(30) pp. 7335–7343.

Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells

Added 26 July, 2012

Kimani, Stanley ; Shmigol, Tatiana; Hammond, Samantha ; Phillips, James B. ; Bruce, James I. ; MacRobert, Alexander J.; Malakhov, Mikhail V. and Golding, Jon P. (2013). Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells. Photochemistry and Photobiology, 89(1) pp. 139–149.

Micro-structured materials and mechanical cues in 3D collagen gels

Added 19 July, 2012

Phillips, James and Brown, Robert (2010). Micro-structured materials and mechanical cues in 3D collagen gels. In: Haycock, John W. ed. 3D Cell Culture. Methods in Molecular Biology (695). New York: Humana Press, pp. 183–196.

Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model

Added 11 July, 2012

Wright, Kathleen E. ; MacRobert, Alexander J. and Phillips, James B. (2012). Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model. Photochemistry and Photobiology, 88 pp. 1539–1545.

Engineering an integrated cellular interface in three-dimensional hydrogel cultures permits monitoring of reciprocal astrocyte and neuronal responses

Added 15 February, 2012

East, Emma ; Golding, Jon P. and Phillips, James B. (2012). Engineering an integrated cellular interface in three-dimensional hydrogel cultures permits monitoring of reciprocal astrocyte and neuronal responses. Tissue Engineering Part C: Methods, 18(7) pp. 526–536.

Antioxidant inhibitors potentiate the cytotoxicity of photodynamic therapy

Added 16 November, 2011

Kimani, Stanley G. ; Phillips, James B. ; Bruce, James I. ; MacRobert, Alexander J. and Golding, Jon P. (2012). Antioxidant inhibitors potentiate the cytotoxicity of photodynamic therapy. Photochemistry and Photobiology, 88(1) pp. 175–187.

An ultrastructural and biochemical analysis of collagen in rat peripheral nerves: the relationship between fibril diameter and mechanical properties

Added 21 October, 2011

Mason, Sarah and Phillips, James (2011). An ultrastructural and biochemical analysis of collagen in rat peripheral nerves: the relationship between fibril diameter and mechanical properties. Journal of the Peripheral Nervous System, 16(3) pp. 261–269.

Micro-structured materials and mechanical cues in 3D collagen gels

Added 21 January, 2011

Phillips, James and Brown, Robert (2010). Micro-structured materials and mechanical cues in 3D collagen gels. In: Haycock, John W. ed. 3D Cell Culture. Methods in Molecular Biology (695). New York: Humana Press (Springer Verlag), pp. 183–196.

Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit

Added 18 August, 2010

East, Emma ; Blum de Oliveira, Daniela; Golding, Jon P. and Phillips, James B. (2010). Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit. Tissue Engineering Part A, 16(10) pp. 3173–3184.

The neuroprotective effects of fibronectin mats and fibronectin peptides following spinal cord injury in the rat

Added 28 May, 2010

King, V. R.; Hewazy, D.; Alovskaya, A.; Phillips, J. B. ; Brown, R. A. and Priestley, J. V. (2010). The neuroprotective effects of fibronectin mats and fibronectin peptides following spinal cord injury in the rat. Neuroscience, 168(2) pp. 523–530.

A versatile 3D culture model facilitates monitoring of astrocytes undergoing reactive gliosis

Added 21 October, 2009

East, Emma ; Golding, Jonathan P. and Phillips, James B. (2009). A versatile 3D culture model facilitates monitoring of astrocytes undergoing reactive gliosis. Journal of Tissue Engineering and Regenerative Medicine, 3(8) pp. 634–646.

Investigating the mechanical shear-plane between core and sheath elements of peripheral nerves

Added 16 September, 2009

Georgeu, G. A.; Walbeehm, E. T.; Tillett, R.; Afoke, A.; Brown, R. A. and Phillips, J. B. (2005). Investigating the mechanical shear-plane between core and sheath elements of peripheral nerves. Cell and Tissue Research, 320(2) pp. 229–234.

Host muscle cell infiltration in cell-seeded plastic compressed collagen constructs.

Added 7 September, 2009

H. Kayhanian, S. Jones, J.B. Phillips, M. Lewis, R. Brown and V. Mudera (2009) Host muscle cell infiltration in cell-seeded plastic compressed collagen constructs. Journal of Tissue Engineering and Regenerative Medicine, 3, 72-75.

Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model

Added 30 July, 2009

Wright, K. E. ; Liniker, E.; Loizidou, M.; Moore, C.; MacRobert, A. J. and Phillips, J. B. (2009). Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model. British Journal of Cancer, 101(4) pp. 658–665.

Host muscle cell infiltration in cell-seeded plastic compressed collagen constructs

Added 19 November, 2008

Kayhanian, Hamzeh; Jones, Stephanie; Phillips, James ; Lewis, Mark; Brown, Robert and Mudera, Vivek (2009). Host muscle cell infiltration in cell-seeded plastic compressed collagen constructs. Journal of Tissue Engineering and Regenerative Medicine, 3(1) pp. 72–75.

Tissue engineered cell culture models for nervous system research

Added 20 October, 2008

East, Emma and Phillips, James B. (2008). Tissue engineered cell culture models for nervous system research. In: Greco, Giovanni N. ed. Tissue Engineering Research Trends. Nova Science Publishers, Inc, pp. 141–160.

Fibronectin, Collagen, Fibrin – Components of Extracellular Matrix for Nerve Regeneration

Added 26 September, 2007

Alovskaya, A; Alekseeva, T; Phillips, JB; King, V and Brown, R (2007). Fibronectin, Collagen, Fibrin - Components of Extracellular Matrix for Nerve Regeneration. In: Ashammakhi, N.; Reis, R. L. and Chiellini, E. eds. Topics in tissue engineering, Volume 3. Biomaterials and Tissue Engineering Group.

Cell responses to biomimetic protein scaffolds used in tissue repair and engineering

Added 27 June, 2007

Brown, Robert A. and Phillips, James B. (2007). Cell responses to biomimetic protein scaffolds used in tissue repair and engineering. International Review of Cytology, 262 pp. 75–150.

Characterization of non-neuronal elements within fibronectin mats implanted into the damaged spinal cord

Added 7 May, 2006

V.R. King, J.B. Phillips, H. Hunt-Grubbe, R. Brown, and J.V. Priestley (2006) Characterization of non-neuronal elements within fibronectin mats implanted into the damaged spinal cord. Biomaterials 27, 485-496.

Serum deprivation and re-addition: Effects on cyclooxygenase inhibitor sensitivity in cultured glia

Added 6 February, 2005

J.B. Phillips and B. Pearce (2005) Serum deprivation and re-addition: Effects on cyclooxygenase inhibitor sensitivity in cultured glia. Inflammopharmacology 13, 431-439.

Neural tissue engineering: A self-organizing collagen guidance conduit.

Added 6 January, 2005

J.B. Phillips, S. Bunting, S.M. Hall and R.A. Brown (2005) Neural tissue engineering: A self-organizing collagen guidance conduit. Tissue Engineering 11, 1611-1617

Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering.

Added 27 June, 2004

Phillips, James B.; King, Von R.; Ward, Zoë; Porter, Rebecca A.; Priestley, John V. and Brown, Robert A. (2004). Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering. Biomaterials, 25(14) pp. 2769–2779.

The effects of treatment with antibodies to transforming growth factor β1 and β2 following spinal cord damage.

Added 6 March, 2004

V.R. King, J.B. Phillips, R.A. Brown, and J.V. Priestley (2004) The effects of treatment with antibodies to transforming growth factor β1 and β2 following spinal cord damage. Neuroscience 126, 173-183

Peripheral nerves exhibit localised heterogeneity of tensile properties during limb movement

Added 6 February, 2004

J.B. Phillips, X. Smit, N. De Zoysa, A. Afoke, and R.A. Brown (2004) Peripheral nerves exhibit localised heterogeneity of tensile properties during limb movement. Journal of Physiology 557, 879-87.

Investigating mechanical behaviour at a core-sheath interface in peripheral nerves

Added 6 January, 2004

R.L. Tillett, A. Afoke, S.M. Hall, R.A. Brown and J.B. Phillips (2004) Investigating mechanical behaviour at a core-sheath interface in peripheral nerves. Journal of the Peripheral Nervous System 9, 255-262.

Conference Items

Label free optical imaging of engineered neural tissue formation by second harmonic signals from collagen type I

Added 11 November, 2014

Sanen, K. ; Paesen, R.; Martens, W. ; Lambrichts, I.; Phillips, J. B. and Ameloot, M. (2014). Label free optical imaging of engineered neural tissue formation by second harmonic signals from collagen type I. In: 18th International Microscopy Congress, 7-12 September 2014, Prague.

A mathematical framework for nerve regeneration in implantable conduits

Added 11 November, 2014

Evans, O. R.; Phillips, J. B. and Shipley, R. J. (2014). A mathematical framework for nerve regeneration in implantable conduits. In: 2014 Annual Tissue & Cell Engineering Society Meeting, 2-4 July 2014, Newcastle, U.K., p. 106.

Adapting aligned stabilised hydrogels to facilitate large scale drug screening and neurobiological research.

Added 8 October, 2014

O'Rourke, Caitriona ; Drake, Rosemary; Loughlin, Jane and Phillips, James (2013). Adapting aligned stabilised hydrogels to facilitate large scale drug screening and neurobiological research. In: Future Investigators Of Regenerative Medicine Symposium, 30 Sept – 03 Oct, 2013, Platja d'Aro, Spain.

Adapting aligned, stabilised 3D tissues for large-scale neurobiological research

Added 8 October, 2014

O'Rourke, Caitriona ; Drake, Rosemary; Loughlin, Jane and Phillips, James (2014). Adapting aligned, stabilised 3D tissues for large-scale neurobiological research. In: Tissue and Cell Engineering Society Annual Conference 2014, 2-4 July 2014, Newcastle, p. 29.

Development of stabilised aligned CNS co-culture technology to model the behaviour of a range of neural cell types

Added 9 July, 2014

O'Rourke, Caitriona ; Loughlin, Jane ; Drake, Rosemary and Phillips, James (2014). Development of stabilised aligned CNS co-culture technology to model the behaviour of a range of neural cell types. In: 3D Cell Culture 2014, 25-27 June 2014, Freiburg Germany.

Aligned Schwann cells derived from human dental pulp stem cells direct neurite growth in a tissue engineered collagen construct

Added 8 July, 2013

Sanen, Kathleen ; Martens, Wendy ; Georgiou, Melanie ; Phillips, James ; Lambrichts, Ivo and Ameloot, Marcel (2013). Aligned Schwann cells derived from human dental pulp stem cells direct neurite growth in a tissue engineered collagen construct. In: XI European Meeting on Glial Cells in Health and Disease, 3-6 July 2013, Berlin, Germany.

Fabrication of an endoneurium using engineered neural tissue within a peripheral nerve repair conduit

Added 2 July, 2013

Georgiou, Melanie ; Golding, Jon ; Loughlin, Jane and Phillips, James (2013). Fabrication of an endoneurium using engineered neural tissue within a peripheral nerve repair conduit. In: Tissue Engineering and Regenerative Medicine International Society - EU Meeting, 17-20 June 2013, Istanbul, Turkey.

Engineered neural tissue as a substitute for the autograft in peripheral nerve repair

Added 2 July, 2013

Phillips, James (2013). Engineered neural tissue as a substitute for the autograft in peripheral nerve repair. In: Tissue Engineering and Regenerative Medicine International Society - EU Meeting, 17-20 June 2013, Istanbul, Turkey.

A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies

Added 25 April, 2013

O'Rourke, Caitriona ; Loughlin, A. J. ; Drake, Rosemary and Phillips, J. B. (2013). A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies. In: BNA Festival of Neuroscience, 07-10 April 2013, London.

Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro

Added 5 February, 2013

O'Rourke, C. ; Loughlin, J. ; Drake, R. and Phillips, J. B. (2012). Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro. In: Neuroscience 2012, 13 - 17 October 2012, New Orleans.

A living replacement tissue for peripheral nerve that can enhance regeneration in vitro and in vivo

Added 13 September, 2012

Georgiou, Melanie ; Bunting, Stephen ; Golding, Jon ; Loughlin, Jane and Phillips, James (2012). A living replacement tissue for peripheral nerve that can enhance regeneration in vitro and in vivo. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Vienna, Austria.

Novel technology for simple assembly of aligned 3D cellular collagen materials for tissue engineering

Added 13 September, 2012

Phillips, James and Drake, Rosemary (2012). Novel technology for simple assembly of aligned 3D cellular collagen materials for tissue engineering. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Vienna, Austria.

A nerve repair conduit containing differentiated adipose-derived stem cells within engineered neural tissue can support and guide neuronal growth in vitro and in vivo

Added 13 September, 2012

Georgiou, Melanie ; Kingham, Paul; Bunting, Stephen ; Golding, Jon ; Loughlin, Jane and Phillips, James (2012). A nerve repair conduit containing differentiated adipose-derived stem cells within engineered neural tissue can support and guide neuronal growth in vitro and in vivo. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Vienna, Austria.

Optimising glial cell alignment in 3D culture to facilitate the development of neural tissue models for CNS research

Added 11 September, 2012

O'Rourke, Caitriona ; Loughlin, Jane ; Drake, Rosemary and Phillips, James (2012). Optimising glial cell alignment in 3D culture to facilitate the development of neural tissue models for CNS research. In: Tissue Engineering and Regenerative Medicine International Society - World Congress 2012, 5 - 8 September 2012, Austria, Vienna.

Engineered neural tissue with columns of aligned Schwann cell-like cells from differentiated adipose-derived stem cells can support and guide neuronal growth in vitro

Added 30 August, 2012

Georgiou, Melanie ; Kingham, Paul; Golding, Jon ; Loughlin, Jane and Phillips, James (2012). Engineered neural tissue with columns of aligned Schwann cell-like cells from differentiated adipose-derived stem cells can support and guide neuronal growth in vitro. In: 3rd International Conference on Stem Cell Engineering "Designing Cellular Therapies", 29 April - 02 May 2012, Seattle, US.

Engineered neural tissue with aligned Schwann cells supports neuronal regeneration in vivo and can be assembled using differentiated adipose-derived stem cells

Added 11 July, 2012

Georgiou, M. ; Loughlin, J. ; Golding, J. P. ; Kingham, P. J. and Phillips, J. B. (2012). Engineered neural tissue with aligned Schwann cells supports neuronal regeneration in vivo and can be assembled using differentiated adipose-derived stem cells. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK.

Defining glial cell self-alignment parameters for 3D CNS tissue models

Added 11 July, 2012

O'Rourke, C. M. ; Loughlin, A. J. ; Drake, R. and Phillips, J. B. (2012). Defining glial cell self-alignment parameters for 3D CNS tissue models. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK.

Astrocytes expressing GFP in 3D collagen gels provide an effective model for screening the glial response to potential CNS cell therapies

Added 11 July, 2012

Johns, N. ; East, E. ; Golding, J. P. ; Loughlin, A. J. and Phillips, J. B. (2012). Astrocytes expressing GFP in 3D collagen gels provide an effective model for screening the glial response to potential CNS cell therapies. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK.

Developing a 3D co-culture model to simulate perinatal hypoxic-ischaemic brain injury in preterm infants

Added 11 July, 2012

Osei, E. T.; Evans, L.; Phillips, J. B. and Loughlin, A. J. (2012). Developing a 3D co-culture model to simulate perinatal hypoxic-ischaemic brain injury in preterm infants. In: Annual meeting of the Tissue and Cell Engineering Society (TCES), 4-6 July 2012, Liverpool, UK.

Aligned Schwann cells within 3D tissue-like gels provide guidance to regenerating neurites

Added 20 September, 2011

Georgiou, M. ; East, E. ; Loughlin, J. ; Golding, J. and Phillips, J. (2011). Aligned Schwann cells within 3D tissue-like gels provide guidance to regenerating neurites. In: 10th European Meeting on Glial Cells in Health and Disease, 13-17 September 2011, Prague, Czech Republic.

Monitoring glial cell behaviour and neuron-glial interactions in 3D hydrogel and aggregate culture systems

Added 20 September, 2011

Phillips, J. and Loughlin, J. (2011). Monitoring glial cell behaviour and neuron-glial interactions in 3D hydrogel and aggregate culture systems. In: 10th European Meeting on Glial Cells in Health and Disease, 13-17 September 2011, Prague, Czech Republic.

Schwann cells in collagen gels survive plastic compression and maintain their alignment: development of a cellular biomaterial for peripheral nerve repair

Added 20 September, 2011

Georgiou, M. ; East, E. ; Loughlin, J. ; Golding, J.P. and Phillips, J.B. (2010). Schwann cells in collagen gels survive plastic compression and maintain their alignment: development of a cellular biomaterial for peripheral nerve repair. In: Tissue and Cell Engineering Society, 28-30th July, Manchester, U.K..

Development of an integrated collagen gel system for studying cellular interfaces following spinal cord injury

Added 20 September, 2011

East, E. ; Golding, J.P. and Phillips, J.B. (2010). Development of an integrated collagen gel system for studying cellular interfaces following spinal cord injury. In: Tissue and Cell Engineering Society, 28-30th July, Manchester, U.K..

Investigating the role of collagen in the biomechanical behaviour of peripheral nerves

Added 20 September, 2011

Mason, S. and Phillips, J. (2010). Investigating the role of collagen in the biomechanical behaviour of peripheral nerves. In: Tissue and Cell Engineering Society, 28-30th July, Manchester, U.K..

Plastic compression of aligned cellular collagen gels for nervous system repair

Added 20 September, 2011

East, E. ; Georgiou, M. ; Loughlin, A.J. ; Golding, J.P. and Phillips, J.B. (2010). Plastic compression of aligned cellular collagen gels for nervous system repair. In: Tissue Engineering and Regenerative Medicine International Society - EU Meeting, 13-17th June, Galway, Ireland.

An ultrastructural and histological investigation of structural features related to biomechanical properties of human peripheral nerves at joint and non joint regions

Added 8 September, 2011

Phillips, J. B. and Mason, S. (2011). An ultrastructural and histological investigation of structural features related to biomechanical properties of human peripheral nerves at joint and non joint regions. In: 2011 PNS Biennial Meeting of the Peripheral Nerve Society, 25-29 June 2011, Potomac, Maryland, US.

A tissue engineered 3D culture model for studying damage and repair in peripheral nerves

Added 8 September, 2011

Phillips, J. B. (2011). A tissue engineered 3D culture model for studying damage and repair in peripheral nerves. In: 2011 PNS Biennial Meeting of the Peripheral Nerve Society, 25-29 June 2011, Potomac, Maryland, US.

A tissue engineered collagen conduit containing columns of aligned Schwann cells supports neuronal regeneration in vitro

Added 8 September, 2011

Georgiou, M., East, E., Loughlin, A. J., Golding, J. P. and Phillips, J. B. (2011). A tissue engineered collagen conduit containing columns of aligned Schwann cells supports neuronal regeneration in vitro. In: 2011 PNS Biennial Meeting of the Peripheral Nerve Society, 25-29 June 2011, Potomac, Maryland, US.

3d micro-structured collagen conduits for nerve repair

Added 25 July, 2011

Karamsadkar, S., Alekseeva, T., Bunting, S., Stomati, K., Cheema, U., Georgiou, M., Phillips, J., Brown, R. A. and Priestley, J. V (2011). 3d micro-structured collagen conduits for nerve repair. In: Tissue Engineering & Regenerative Medicine International Society, 7-10 June 2011, Granada, Spain.

Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants.

Added 25 July, 2011

East, E., Murphy, K. and Phillips, J. (2011). Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants. In: Tissue and Cell Engineering Society, 19-21 July 2011, Leeds.

Aligned cellular and acellular collagen guidance substrates for peripheral nerve repair

Added 25 July, 2011

Georgiou, Melanie; Loughlin, Jane; Golding, Jon and Phillips, James (2011). Aligned cellular and acellular collagen guidance substrates for peripheral nerve repair. In: Tissue and Cell Engineering Society, 19 - 21 July 2011, Leeds.

Potentiation of AlPcS2 mediated photodynamic therapy by energy metabolism inhibitors in human tumour cell lines

Added 20 January, 2011

Kimani, Stanley; Phillips, James; Bruce, James; MacRobert, A. J. and Golding, Jon (2009). Potentiation of AlPcS2 mediated photodynamic therapy by energy metabolism inhibitors in human tumour cell lines. In: 13th Congress of the European Society for Photobiology, 5 Sep 2009, Warsaw, Poland.

Keynote: tissue engineering to model and repair the nervous system

Added 20 January, 2011

Phillips, James (2009). Keynote: tissue engineering to model and repair the nervous system. In: Tissue and Cell Engineering Society, 8-10 July 2009, Glasgow, UK.

Glucosamine improves the efficiency of photodynamic therapy (PDT)

Added 13 January, 2011

Kimani, Stanley; Phillips, James; Bruce, James; MacRobert, A. J and Golding, Jon (2008). Glucosamine improves the efficiency of photodynamic therapy (PDT). In: Photodynamic Therapy and Photodiagnosis in Clinical Practice, 7- 11 Oct 2008, Brixen, Italy.

Collagen fibril diameter variation correlates with biomechanical heterogeneity in peripheral nerves

Added 22 June, 2010

Mason, Sarah and Phillips, James (2010). Collagen fibril diameter variation correlates with biomechanical heterogeneity in peripheral nerves. In: Proceedings of the International Anatomical Sciences and Cell Biology Conference, 26 - 29 May 2010, National University of Singapore, Singapore.

The role of cellular antioxidant pathways in protecting neurons during photodynamic therapy

Added 16 December, 2009

Phillips, James; Wright, Kathleen and MacRobert, Alexander (2009). The role of cellular antioxidant pathways in protecting neurons during photodynamic therapy. In: First International Conference On Metal Chelation in Biology & Medicine, 11-14 December 2009, Bath, UK.

Regenerative capacity of cultured neurons following photodynamic therapy in a 3D collagen gel culture system

Added 15 December, 2009

Wright, K. E. and Phillips, J. B. (2009). Regenerative capacity of cultured neurons following photodynamic therapy in a 3D collagen gel culture system. European Cells and Materials, 18(Sup 2) p. 112.

Characterising regional ultrastructure in peripheral nerves

Added 15 December, 2009

Mason, S.; Harle, J. and Phillips, J. B. (2009). Characterising regional ultrastructure in peripheral nerves. European Cells and Materials, 18(Sup 2) p. 77.

Tissue engineering to model and repair the nervous system

Added 15 December, 2009

Phillips, J. (2009). Tissue engineering to model and repair the nervous system. European Cells and Materials, 18(Supp 2) p. 17.

Astrocyte alignment in 3D collagen gels increases neurite outgrowth; implications for improving spinal cord repair

Added 15 December, 2009

East, E.; Blum de Oliveira, D.; Golding, J. P. and Phillips, J. B. (2009). Astrocyte alignment in 3D collagen gels increases neurite outgrowth; implications for improving spinal cord repair. European Cells and Materials, 18(Sup 2) p. 13.

Astrocyte alignment increases neurite outgrowth in a 3D cell culture model

Added 8 October, 2009

East, Emma <http://oro.open.ac.uk/view/person/ee648.html>; Blum de Oliveira, Daniela; Golding, Jon <http://oro.open.ac.uk/view/person/jpg259.html> and Phillips, James <http://oro.open.ac.uk/view/person/jbp52.html> (2009). Astrocyte alignment increases neurite outgrowth in a 3D cell culture model. Glia, 57(S13) S159.

Developing a 3D culture model of CNS myelination

Added 8 October, 2009

Loughlin, Jane <http://oro.open.ac.uk/view/person/ajl75.html>; East, Emma <http://oro.open.ac.uk/view/person/ee648.html>; Golding, Jon <http://oro.open.ac.uk/view/person/jpg259.html> and Phillips, James <http://oro.open.ac.uk/view/person/jbp52.html> (2009). Developing a 3D culture model of CNS myelination. Glia, 57(S13) S119.

Keynote: Tissue engineered approaches to modelling the nervous system

Added 21 April, 2009

Phillips, James (2009). Keynote: Tissue engineered approaches to modelling the nervous system. In: NC3Rs/BBSRC Symposium – Tissue engineering: a new dimension to animal replacement, 1-2 April 2009, London, UK.

Monitoring reactive gliosis in 3-dimensional astrocyte cultures; a model of spinal cord damage

Added 21 January, 2009

Phillips, James; East, Emma and Golding, Jon (2008). Monitoring reactive gliosis in 3-dimensional astrocyte cultures; a model of spinal cord damage. In: Neuroscience 2008: 38th annual meeting of the Society for Neuroscience, 15-19 Nov 2008, Washington, DC.

Differences in sensitivity to mTHPC-mediated photodynamic therapy of neurons, glial cells and MCF7 cells in a 3-dimensional cell culture model

Added 22 October, 2008

Wright, K. E.; MacRobert, A. J. and Phillips, J. B. (2008). Differences in sensitivity to mTHPC-mediated photodynamic therapy of neurons, glial cells and MCF7 cells in a 3-dimensional cell culture model. In: Photodynamic Therapy and Photodiagnosis in Clinical Practice, 7- 11 October 2008, Brixen, Italy.

Modelling the injured spinal cord using 3-dimensional cell cultures; strategies for improving tissue engineered repair

Added 19 August, 2008

East, E.; Golding, J. P. and Phillips, J. B. (2008). Modelling the injured spinal cord using 3-dimensional cell cultures; strategies for improving tissue engineered repair. European Cells and Materials, 16(Supple) p. 51.

Investigating the role of collagen in peripheral nerve biomechanics

Added 19 August, 2008

Mason, S.; Harle, J. and Phillips, J. B. (2008). Investigating the role of collagen in peripheral nerve biomechanics. European Cells and Materials, 16(Supple), p. 80.

Modelling of the injured spinal cord using 3-dimensional cell cultures; strategies for improving tissue engineered repair

Added 20 November, 2007

East, E.; Golding, J.P. and Phillips, J.B. (2007). Modelling of the injured spinal cord using 3-dimensional cell cultures; strategies for improving tissue engineered repair. In: Society for Neuroscience, 3-7 Nov 2007, San Diego, California.

Increased GFAP immunoreactivity by astrocytes in response to contact with dorsal root ganglia cells in a 3D culture model

Added 14 October, 2007

East, Emma; Golding, Jon and Phillips, James (2007). Increased GFAP immunoreactivity by astrocytes in response to contact with dorsal root ganglia cells in a 3D culture model. Neuron Glia Biology, 3(S1) S119.

Development of a 3-dimensional in vitro model to study reactive gliosis following nervous system injury

Added 14 October, 2007

East, Emma; Golding, Jon and Phillips, James (2007). Development of a 3-dimensional in vitro model to study reactive gliosis following nervous system injury. Tissue Engineering, 13(7) p. 1668.

Increased GFAP immunoreactivity by astrocytes in response to contact with dorsal root ganglia cells in a 3D culture model

Added 20 September, 2007

East, Emma; Golding, Jon and Phillips, James (2007). Increased GFAP immunoreactivity by astrocytes in response to contact with dorsal root ganglia cells in a 3D culture model. In: Glial cells in health and disease, 4-8 September 2007, London, UK.

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