An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells

An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells

C. O’Rourke, A. G. E. Day, C. Murray-Dunning, L. Thanabalasundaram, J. Cowan, L. Stevanato, N. Grace, G. Cameron, R. A. L. Drake, J. Sinden & J. B. Phillips (2018) An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells. Scientific Reports 8, 2951

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New Publication: ‘Off the shelf’ living replacement nerve tissue

This paper reports a study in which engineered neural tissue (EngNT) was made using ReNeuron‘s clinical grade stem cells and tested in a nerve injury model using athymic nude rats. This approach offers the possibility of developing an Advanced Therapy Medicinal Product (ATMP) using allogeneic cells which could potentially be suitable for implantation into patients […]

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PhD Studentship in Nerve Tissue Engineering

A PhD studentship is available entitled “Combining Therapeutic Cells and Biomaterials to Develop Engineered Tissue for Repairing Peripheral Nerves”. For more details visit the UCL studentship page.

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Controlling human corneal stromal stem cell contraction to mediate rapid cell and matrix organization of real architecture for 3-dimensional tissue equivalents

Mukhey D, Phillips JB, Daniels JT, Kureshi AK (2018) Controlling human corneal stromal stem cell contraction to mediate rapid cell and matrix organization of real architecture for 3-dimensional tissue equivalents. Acta Biomaterialia. 2018 Feb;67:229-237

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