Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy

Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy

Golding, J. P. ; Wardhaugh, T. ; Patrick, L.; Turner, M.; Phillips, J. B. ; Bruce, J. I. and Kimani, S. G. (2013). Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy. British Journal of C…

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New Paper: Engineered Neural Tissue for Peripheral Nerve Repair

Published online in Biomaterials on 5th July, this paper describes the construction and testing of living artificial nerve tissue that could potentially be used in regenerative medicine to repair peripheral nerves. The Engineered Neural Tissue is made by organising Schwann cells and collagen into robust sheets of aligned cellular material that support and guide neuronal […]

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Engineered neural tissue for peripheral nerve repair

Georgiou, Melanie ; Bunting, Stephen C. J. ; Davies, Heather A. ; Loughlin, Alison J. ; Golding, Jonathan P. and Phillips, James B. (2013). Engineered neural tissue for peripheral nerve repair. Biomaterials, 34(30) pp. 7335–7343.

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Aligned Schwann cells derived from human dental pulp stem cells direct neurite growth in a tissue engineered collagen construct

Sanen, Kathleen ; Martens, Wendy ; Georgiou, Melanie ; Phillips, James ; Lambrichts, Ivo and Ameloot, Marcel (2013). Aligned Schwann cells derived from human dental pulp stem cells direct neurite growth in a tissue engineered collagen construct. In…

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Fabrication of an endoneurium using engineered neural tissue within a peripheral nerve repair conduit

Georgiou, Melanie ; Golding, Jon ; Loughlin, Jane and Phillips, James (2013). Fabrication of an endoneurium using engineered neural tissue within a peripheral nerve repair conduit. In: Tissue Engineering and Regenerative Medicine International So…

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Engineered neural tissue as a substitute for the autograft in peripheral nerve repair

Phillips, James (2013). Engineered neural tissue as a substitute for the autograft in peripheral nerve repair. In: Tissue Engineering and Regenerative Medicine International Society – EU Meeting, 17-20 June 2013, Istanbul, Turkey.

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Oral presentation prize at Cell-Based Therapy symposium

Kathleen Sanen (collaborating PhD student at Hasselt University, Belgium) was awarded the prize for best oral presentation at the Cell-based therapies in central nervous system pathology symposium on April 12th 2013. This symposium covered a series of biological subjects relating to stem cells, their involvement in brain disease and trauma and their potential use in regenerative […]

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A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies

O’Rourke, Caitriona ; Loughlin, A. J. ; Drake, Rosemary and Phillips, J. B. (2013). A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies. In: BNA Festival of Neuroscience, 07-10 April 2013, London. …

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New European Collaboration with Hasselt University, Belgium

The group is working closely with researchers from the Biomedical Research Institute (BIOMED) at Hasselt University on a new translational project in the field of peripheral nerve injury. The project has already involved two BIOMED researchers, Kathleen Sanen and Dr Wendy Martens, working in our labs at the OU. Kathleen is a PhD student in the Biophysics […]

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Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro

O’Rourke, C. ; Loughlin, J. ; Drake, R. and Phillips, J. B. (2012). Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro. In: Neuroscience 2012, 13 – 17 October 2012…

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