PhD Success

Congratulations to Stanley Kimani who successfully passed his PhD viva examination on 25th March. Stan’s PhD thesis title is “Exploiting tumour metabolism to augment the cytotoxicity of photodynamic therapy and to develop novel photosensitizers” and his interdisciplinary project used cell culture systems and synthetic chemistry to explore potential methods for improving cancer therapy.

Micro-structured materials and mechanical cues in 3D collagen gels

Phillips, James and Brown, Robert (2010). Micro-structured materials and mechanical cues in 3D collagen gels. In: Haycock, John W. ed. 3D Cell Culture. Methods in Molecular Biology (695). New York: Humana Press (Springer Verlag), pp. 183–196.

Potentiation of AlPcS2 mediated photodynamic therapy by energy metabolism inhibitors in human tumour cell lines

Kimani, Stanley; Phillips, James; Bruce, James; MacRobert, A. J. and Golding, Jon (2009). Potentiation of AlPcS2 mediated photodynamic therapy by energy metabolism inhibitors in human tumour cell lines. In: 13th Congress of the European Society for…

Keynote: tissue engineering to model and repair the nervous system

Phillips, James (2009). Keynote: tissue engineering to model and repair the nervous system. In: Tissue and Cell Engineering Society, 8-10 July 2009, Glasgow, UK.

Glucosamine improves the efficiency of photodynamic therapy (PDT)

Kimani, Stanley; Phillips, James; Bruce, James; MacRobert, A. J and Golding, Jon (2008). Glucosamine improves the efficiency of photodynamic therapy (PDT). In: Photodynamic Therapy and Photodiagnosis in Clinical Practice, 7- 11 Oct 2008, Brixen, It…

RSC Lecture

Melanie Georgiou delivered a talk “Engineering functional tissues for regenerative medicine: development of a cellular implant for nerve repair” at the Royal Society of Chemistry Prize and Award Lecture event at the OU on 12th January [view the programme]

3D Cell culture Book Chapter

Micro-Structured Materials and Mechanical Cues in 3D Collagen Gels (James Phillips & Robert Brown) Chapter 12 in the new Methods in Molecular Biology book “3D Cell Culture” Edited by John Haycock.

Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit

East, Emma ; Blum de Oliveira, Daniela; Golding, Jon P. and Phillips, James B. (2010). Alignment of astrocytes increases neuronal growth in three-dimensional collagen gels and is maintained following plastic compression to form a spinal cord repai…

Tissue Engineering Paper: 3D astrocyte alignment increases neuron growth

Alignment of astrocytes increases neuronal growth in 3D collagen gels and is maintained following plastic compression to form a spinal cord repair conduit We have published a paper showing that alignment of astrocytes in 3D culture makes them more permissive for neuron growth than unaligned cells. Astrocytes in the damaged central nervous system surround a […]

Collagen fibril diameter variation correlates with biomechanical heterogeneity in peripheral nerves

Mason, Sarah and Phillips, James (2010). Collagen fibril diameter variation correlates with biomechanical heterogeneity in peripheral nerves. In: Proceedings of the International Anatomical Sciences and Cell Biology Conference, 26 – 29 May 2010, Na…