Nerve repair project awarded prestigious UCL Rosetrees Stoneygate Prize
Nerve repair project awarded prestigious UCL Rosetrees Stoneygate Prize
We are delighted to announce our team was awarded the 2018 UCL Rosetrees Stoneygate Prize for research into improving nerve grafting using biomaterials. This cross-faculty research team led by James Phillips includes Rebecca Shipley, (UCL Mechanical Engineering, UCL Institute of Healthcare Engineering), Ashleigh Boyd (UCL Division of Surgery & Interventional Science, UCL Institute of Immunity […]
Read more »Naked Scientists Podcast
Listen to James and Becky talking about nerve injury and repair in this Naked Scientists Podcast.
Read more »Developing an in vitro model to screen drugs for nerve regeneration
Rayner M, Laranjeira S, Evans RE, Shipley RJ, Healy J & Phillips JB (2018) Developing an in vitro model to screen drugs for nerve regeneration Anatomical Record doi:10.1002/ar.23918
Read more »Vascularisation strategies for peripheral nerve tissue engineering
Muangsanit P, Shipley RJ & Phillips JB (2018) Vascularisation strategies for peripheral nerve tissue engineering. Anatomical Record doi:10.1002/ar.23919
Read more »An optimized collagen-fibrin blend enhances the ability of engineered neural tissue to promote peripheral nerve repair
Schuh CMAP, Day AGE, Redl H & Phillips JB (2018) An optimized collagen-fibrin blend enhances the ability of engineered neural tissue to promote peripheral nerve repair. Tissue Engineering Part A, 24, 1332-1340
Read more »An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells
C. O’Rourke, A. G. E. Day, C. Murray-Dunning, L. Thanabalasundaram, J. Cowan, L. Stevanato, N. Grace, G. Cameron, R. A. L. Drake, J. Sinden & J. B. Phillips (2018) An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells. Scientific Reports 8, 2951
Read more »New Publication: ‘Off the shelf’ living replacement nerve tissue
This paper reports a study in which engineered neural tissue (EngNT) was made using ReNeuron‘s clinical grade stem cells and tested in a nerve injury model using athymic nude rats. This approach offers the possibility of developing an Advanced Therapy Medicinal Product (ATMP) using allogeneic cells which could potentially be suitable for implantation into patients […]
Read more »PhD Studentship in Nerve Tissue Engineering
A PhD studentship is available entitled “Combining Therapeutic Cells and Biomaterials to Develop Engineered Tissue for Repairing Peripheral Nerves”. For more details visit the UCL studentship page.
Read more »Controlling human corneal stromal stem cell contraction to mediate rapid cell and matrix organization of real architecture for 3-dimensional tissue equivalents
Mukhey D, Phillips JB, Daniels JT, Kureshi AK (2018) Controlling human corneal stromal stem cell contraction to mediate rapid cell and matrix organization of real architecture for 3-dimensional tissue equivalents. Acta Biomaterialia. 2018 Feb;67:229-237
Read more »International collaborations generate new EngNT papers
In 2017 we were involved in studies demonstrating further development of Engineered Neural Tissue (EngNT) technology. These included in vivo testing of EngNT made using differentiated dental pulp stem cells in collaboration with colleagues in Hasselt University in Belgium, and two papers exploring the use of different ECM materials and mesenchymal stem cells and Schwann cells in […]
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