Isabel Kingston

Technician and Laboratory Manager

Previous roles:

2013-2021 Lab Technician, UCL Biomaterials and Tissue Engineering Department.

2011-2012 Senior Scientific Officer, Cancer Research UK, Developmental Signalling Laboratory.

2007-2011 Postdoctoral Fellow, Cancer Research UK, Macromolecular Structure and Function Laboratory.

2004-2006 JSPS Postdoctoral Fellow, Yokohama CU.  Drug Design Laboratory.

Qualifications:

2004 PhD ‘Interactions of BspMI with two asymmetric Sequences’ University of Bristol (Funded by BBSRC)

2000 BSc Biochemistry (Hons) 2.1 The University of Liverpool

Publications:

Masi S, Orlandi M, Parkar M, Bhowruth D, Kingston I, O’Rourke C, Virdis A, Hingorani A, Hurel SJ, Donos N, D’Aiuto F, Deanfield J. (2018) Mitochondrial oxidative stress, endothelial function and metabolic control in patients with type II diabetes and periodontitis: A randomised controlled clinical trial. Int J Cardiol 15;271:263-268

Grönroos E, Kingston IJ, Ramachandran A, Randall RA, Vizán P, Hill CS. (2012) Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes. Mol Cell Biol;32(14):2904-16

Kingston IJ, Yung JS, Singleton MR, (2011) Biophysical characterization of the centromere-specific nucleosome from budding yeast. J Biol Chem. 4;286(5):4021-6

Amaro AC, Samora CP, Holtackers R, Wang E, Kingston IJ, Alonso M, Lampson M, McAnish AD & Meraldi P (2010). Molecular control of kinetochore-microtubule dynamics and chromosome oscillations.  Nat. Cell. Biol. 12, 319-329

Kingston, I. J., Gormley, N. A. & Halford, S. E. (2003). DNA supercoiling enables the Type IIS restriction enzyme BspMI to recognize the relative orientation of two DNA sequences. Nuc. Acid Res. 31, 5221-5228