Richard Bartlett

RichardProject: Tissue-engineering and regenerative medicine approaches to stabilise, protect and repair the damaged CNS

Richard is a medical student taking time out of the conventional medical course to pursue higher research as part of the MBPhD programme.

He completed his intercalated iBSc in ‘Surgical Sciences’ at UCL in 2014, graduating with a 1st class honours degree and topping his class to win both the Ken-Hobbs Prize and the award for the Best Research Presentation and Viva Voce. Combined, these led to his nomination to the prestigious Dean’s List.

Richard has always had a keen interest in surgery, and as part of his iBSc research project investigated ways in which neurosurgical electrodes could be modified to improve long-term biocompatibility. Under the excellent supervision of Dr Brian Cousins, he went on to present this work nationally and internationally, whereby he won 1st prize at the GSTT surgical assembly and was shortlisted for the prestigious ASiT Medal.

Following on from his iBSc, Richard went on to complete the first year of clinical medicine. During this period he served as President of the UCLU Surgical Society and organised a national surgical conference (NUGSC 2015). This hosted close to 200 delegates and welcomed prestigious guest speakers, including several council members of the Royal College of Surgeons, England.

Qualifications:

iBSc Medical Sciences with Surgical Science – 1st class (Dean’s List)

MBBS – pending 2020

MBPhD – pending 2018

Research:

During his PhD, Richard aims to build-on the work he conducted as part of his undergraduate research, by investigating ways in which tissue-engineered therapies and regenerative medicine might one day be used to repair the damaged central nervous system. Specifically, he hopes to develop clinically competitive therapies able to promote repair in the damaged spinal cord following traumatic injury.

For the first part of his project, he has developed a novel mechanical testing protocol able to robustly characterise the complex viscoelastic behaviours of spinal cord tissue. In doing so, he is now hoping to develop mechanically appropriate tissue-engineered constructs aimed at promoting repair and recovery of function. In particular, he hopes to combine the unique properties of Olfactory Ensheathing Cells (OECs) with supportive biomaterial scaffolds to optimise recovery after injury.

In addition to his PhD research, Richard also has a keen interest in quality improvement. Last year he designed and led a quality improvement project from scratch, and this formed part of the project portfolio which went on to win 1st prize at the National NHS Quality Improvement Championships. He has also recently developed an interactive ECG teaching resource for medical students (link); this was awarded the prestigious Royal Society of Medicine Sidney Linton Prize. Outside of his research, Richard is an avid guitarist and enjoys playing badminton twice weekly. He also has a sustained interest in promoting fairer access to selective courses such as medicine, and in the future aspires to become a research-active neurosurgeon.

Supervisors:
Dr James Phillips – Senior Lecturer in Biomaterials & Tissue Engineering, UCL Eastman Dental Institute
Mr David Choi – Reader in Neurosurgery, UCL Institute of Neurology

Contact email – please feel free to request copies of published articles for personal use

Twitter: @drrdb93

PUBLICATIONS:

Biomechanical properties of the spinal cord: implications for tissue engineering and clinical translation. Bartlett RD, Choi D, Phillips JB. Regenerative Medicine (2016). Link

Probing the biomechanical properties of spinal cord tissue: implications for tissue-engineering (conference proceedings). Bartlett RD, Phillips JB, Choi D. British Journal of Neurosurgery (2016). Link

A novel protocol to characterise the mechanical properties of spinal cord tissue and benchmark candidate biomaterials for CNS tissue-engineering (conference proceedings). Bartlett RD, Choi D, Phillips JB. Vol. 31. Suppl. 1. p8. European Cells and Materials (2016). Link.

Optimisation of Biomaterial Surfaces for Next Generation Neurological Implants (conference proceedings). Bartlett RD, Cousins BG. International Journal of Surgery (2016). Link

Multicentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery. STARSurg DISCOVER Study Collaborator. British Journal of Surgery (2016). Link.

Personalised in vitro cancer modelling – fantasy or reality? Bartlett RD, Everett W, Weiche L, G N, Tan A, Loizidou M, Seifalian A. Translational Oncology (2014). Link.


PRESENTATIONS:
Mapping the viscoelastic mechanical properties of spinal cord tissue: implications for regenerative medicine and tissue engineering in the CNS (oral). Bartlett RD, Choi D, Phillips JB. Tissue & Cell Engineering Society (TCES) 2016, London, UK.

A novel protocol to characterize the mechanical properties of spinal cord tissue and benchmark candidate biomaterials for CNS tissue engineering (poster). Bartlett RD, Choi D, Phillips JB. UCL Neuroscience Symposium 2016, London, UK.

A novel protocol to characterise the mechanical properties of spinal cord tissue and benchmark candidate biomaterials for CNS tissue-engineering (poster). Bartlett RD, Choi D, Phillips JB. Tissue Engineering & Regenerative Medicine International Society (TERMIS) EU-Chapter Meeting 2016, Uppsala, Sweden.

Probing the biomechanical properties of spinal cord tissue: implications for CNS tissue-engineering (oral). Bartlett RD, Phillips JB, Choi D. The British Neurosurgical Research Group Meeting 2016, Cambridge, UK.

Optimisation of Biomaterial Surfaces for Next Generation Neurosurgical Implants (oral). Bartlett RD, Cousins BG. The Association of Surgeons in Training (ASiT) Annual Conference 2015, Glasgow, UK.

Optimisation of Biomaterial Surfaces for Next Generation Neurological Implants (oral). Bartlett RD, Cousins BG. International GSTT Surgical Assembly 2014, London, United Kingdom.

 

INVITED SESSIONS:
Session co-chair: Biomaterials for Pluripotent Stem Cell Culture and Differentiation. Tissue Engineering & Regenerative Medicine International Society (TERMIS) EU-Chapter Meeting 2016, Uppsala, Sweden.

Lecturer: ‘The iBSc Year – The Inside Story’. UCL Medical School 2016, London, UK.

 

AUTHORSHIP:

Primary contributing author for ‘Malaria’ section: Unofficial Guide to Medicine; Eds Byrne P; Qureshi Z, 1st Edition. In progress, publication scheduled 2016.

Primary contributing author for ‘Carpal Tunnel Release Surgery’ section: Unofficial Guide to Surgery; Qureshi Z, 1st Edition. In progress, publication scheduled 2016.

Primary contributing author for ‘Progressive Multifocal Leukoencephalothy’ section: Unofficial Guide to Medicine; Eds Byrne P; Qureshi Z, 1st Edition. In progress, publication scheduled 2016.

Content contributor for soon to launch website www.surgicalteaching.com. Designed talks from scratch on the ‘WHO Checklist’ and ‘Diathermy’. Now invited student consultant.

 

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