A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies

A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies

O’Rourke, Caitriona ; Loughlin, A. J. ; Drake, Rosemary and Phillips, J. B. (2013). A multi-well plate model of reactive gliosis for high throughput screening of potential CNS therapies. In: BNA Festival of Neuroscience, 07-10 April 2013, London. …

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New European Collaboration with Hasselt University, Belgium

The group is working closely with researchers from the Biomedical Research Institute (BIOMED) at Hasselt University on a new translational project in the field of peripheral nerve injury. The project has already involved two BIOMED researchers, Kathleen Sanen and Dr Wendy Martens, working in our labs at the OU. Kathleen is a PhD student in the Biophysics […]

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Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro

O’Rourke, C. ; Loughlin, J. ; Drake, R. and Phillips, J. B. (2012). Stabilisation of hydrogels containing neural cells to form CNS tissue models for monitoring neuronal and glial cell behaviour in vitro. In: Neuroscience 2012, 13 – 17 October 2012…

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A living replacement tissue for peripheral nerve that can enhance regeneration in vitro and in vivo

Georgiou, Melanie ; Bunting, Stephen ; Golding, Jon ; Loughlin, Jane and Phillips, James (2012). A living replacement tissue for peripheral nerve that can enhance regeneration in vitro and in vivo. In: Tissue Engineering and Regenerative Medicine…

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Novel technology for simple assembly of aligned 3D cellular collagen materials for tissue engineering

Phillips, James and Drake, Rosemary (2012). Novel technology for simple assembly of aligned 3D cellular collagen materials for tissue engineering. In: Tissue Engineering and Regenerative Medicine International Society – World Congress 2012, 5 – 8 …

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A nerve repair conduit containing differentiated adipose-derived stem cells within engineered neural tissue can support and guide neuronal growth in vitro and in vivo

Georgiou, Melanie ; Kingham, Paul; Bunting, Stephen ; Golding, Jon ; Loughlin, Jane and Phillips, James (2012). A nerve repair conduit containing differentiated adipose-derived stem cells within engineered neural tissue can support and guide neuro…

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Nerve repair research wins international prize

Melanie Georgiou won first prize for her presentation at the Tissue Engineering & Regenerative Medicine International Society (TERMIS) World Congress in Vienna. Melanie’s abstract was shortlisted for the prestigious Oral Presentation Award Session, during which the five finalists presented their work to an expert panel, who then led a question and answer session in front […]

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Optimising glial cell alignment in 3D culture to facilitate the development of neural tissue models for CNS research

O’Rourke, Caitriona ; Loughlin, Jane ; Drake, Rosemary and Phillips, James (2012). Optimising glial cell alignment in 3D culture to facilitate the development of neural tissue models for CNS research. In: Tissue Engineering and Regenerative Medici…

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New international collaboration to study microglia in 3D culture

We are involved in a new project entitled ‘Remodelling microglia in vitro in a 3D collagen construct’ in collaboration with Dr Sharmili Vidyadaran at Universiti Putra Malaysia. The PhD student working on the project in Dr Vidyadaran’s lab is Tong Chih Kong and financial support has been provided by the Research University Grant Scheme, Universiti Putra Malaysia.

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Engineered neural tissue with columns of aligned Schwann cell-like cells from differentiated adipose-derived stem cells can support and guide neuronal growth in vitro

Georgiou, Melanie ; Kingham, Paul; Golding, Jon ; Loughlin, Jane and Phillips, James (2012). Engineered neural tissue with columns of aligned Schwann cell-like cells from differentiated adipose-derived stem cells can support and guide neuronal gro…

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