Generation of c-MycER-TAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications

Santiago-Toledo G, Georgiou M, dos Reis J, Roberton VH, Valinhas A, Wood RC, Phillips JB, Mason C, Li D, Li Y, Sinden JD, Choi D, Jat PS & Wall IB (2019). Generation of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications. Scientific Reports 9, 13190

The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves

Wilcox M, Quick TJ & Phillips JB (2019) The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves. Frontiers in Cellular Neuroscience 13, 189

Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications

Kayal C, Shipley RJ & Phillips JB (2019) Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications. Journal of the Mechanical Behaviour of Biomedical Materials 99, 216-224

Nerve repair project awarded prestigious UCL Rosetrees Stoneygate Prize

We are delighted to announce our team was awarded the 2018 UCL Rosetrees Stoneygate Prize for research into improving nerve grafting using biomaterials. This cross-faculty research team led by James Phillips includes Rebecca Shipley, (UCL Mechanical Engineering, UCL Institute of Healthcare Engineering), Ashleigh Boyd (UCL Division of Surgery & Interventional Science, UCL Institute of Immunity […]

Naked Scientists Podcast

Listen to James and Becky talking about nerve injury and repair in this Naked Scientists Podcast.

Developing an in vitro model to screen drugs for nerve regeneration

Rayner M, Laranjeira S, Evans RE, Shipley RJ, Healy J & Phillips JB (2018) Developing an in vitro model to screen drugs for nerve regeneration Anatomical Record doi:10.1002/ar.23918

Vascularisation strategies for peripheral nerve tissue engineering

Muangsanit P, Shipley RJ & Phillips JB (2018) Vascularisation strategies for peripheral nerve tissue engineering. Anatomical Record doi:10.1002/ar.23919

An optimized collagen-fibrin blend enhances the ability of engineered neural tissue to promote peripheral nerve repair

Schuh CMAP, Day AGE, Redl H & Phillips JB (2018) An optimized collagen-fibrin blend enhances the ability of engineered neural tissue to promote peripheral nerve repair. Tissue Engineering Part A, 24, 1332-1340

An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells

C. O’Rourke, A. G. E. Day, C. Murray-Dunning, L. Thanabalasundaram, J. Cowan, L. Stevanato, N. Grace, G. Cameron, R. A. L. Drake, J. Sinden & J. B. Phillips (2018) An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells. Scientific Reports 8, 2951

New Publication: ‘Off the shelf’ living replacement nerve tissue

This paper reports a study in which engineered neural tissue (EngNT) was made using ReNeuron‘s clinical grade stem cells and tested in a nerve injury model using athymic nude rats. This approach offers the possibility of developing an Advanced Therapy Medicinal Product (ATMP) using allogeneic cells which could potentially be suitable for implantation into patients […]