Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications

Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications

Kayal C, Shipley RJ & Phillips JB (2019) Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications. Journal of the Mechanical Behaviour of Biomedical Materials 99, 216-224

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Nerve repair project awarded prestigious UCL Rosetrees Stoneygate Prize

We are delighted to announce our team was awarded the 2018 UCL Rosetrees Stoneygate Prize for research into improving nerve grafting using biomaterials. This cross-faculty research team led by James Phillips includes Rebecca Shipley, (UCL Mechanical Engineering, UCL Institute of Healthcare Engineering), Ashleigh Boyd (UCL Division of Surgery & Interventional Science, UCL Institute of Immunity […]

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Naked Scientists Podcast

Listen to James and Becky talking about nerve injury and repair in this Naked Scientists Podcast.

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Developing an in vitro model to screen drugs for nerve regeneration

Rayner M, Laranjeira S, Evans RE, Shipley RJ, Healy J & Phillips JB (2018) Developing an in vitro model to screen drugs for nerve regeneration Anatomical Record doi:10.1002/ar.23918

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Vascularisation strategies for peripheral nerve tissue engineering

Muangsanit P, Shipley RJ & Phillips JB (2018) Vascularisation strategies for peripheral nerve tissue engineering. Anatomical Record doi:10.1002/ar.23919

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An optimized collagen-fibrin blend enhances the ability of engineered neural tissue to promote peripheral nerve repair

Schuh CMAP, Day AGE, Redl H & Phillips JB (2018) An optimized collagen-fibrin blend enhances the ability of engineered neural tissue to promote peripheral nerve repair. Tissue Engineering Part A, 24, 1332-1340

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An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells

C. O’Rourke, A. G. E. Day, C. Murray-Dunning, L. Thanabalasundaram, J. Cowan, L. Stevanato, N. Grace, G. Cameron, R. A. L. Drake, J. Sinden & J. B. Phillips (2018) An allogeneic ‘off the shelf’ therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells. Scientific Reports 8, 2951

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New Publication: ‘Off the shelf’ living replacement nerve tissue

This paper reports a study in which engineered neural tissue (EngNT) was made using ReNeuron‘s clinical grade stem cells and tested in a nerve injury model using athymic nude rats. This approach offers the possibility of developing an Advanced Therapy Medicinal Product (ATMP) using allogeneic cells which could potentially be suitable for implantation into patients […]

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PhD Studentship in Nerve Tissue Engineering

A PhD studentship is available entitled “Combining Therapeutic Cells and Biomaterials to Develop Engineered Tissue for Repairing Peripheral Nerves”. For more details visit the UCL studentship page.

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Controlling human corneal stromal stem cell contraction to mediate rapid cell and matrix organization of real architecture for 3-dimensional tissue equivalents

Mukhey D, Phillips JB, Daniels JT, Kureshi AK (2018) Controlling human corneal stromal stem cell contraction to mediate rapid cell and matrix organization of real architecture for 3-dimensional tissue equivalents. Acta Biomaterialia. 2018 Feb;67:229-237

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